This document represents the consensus of six international agencies regarding broad principles for serving unaccompanied and separated children. The authors take a comprehensive approach focused on preparedness and cooperation, beginning with ways of preserving family unity during an emergency, tracing and family reunification, care arrangements, durable solutions, special concerns for refugee children, and ways of promoting children’s rights. The guidelines provide a succinct compilation of principles for protecting and serving separated children from the beginning of an emergency through arrangement of durable solutions.